Gene Dmel\Gr22d

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General Information

Symbol

Dmel\Gr22d

Species

D. melanogaster

Name

Gustatory receptor 22d

Annotation symbol

CR31930

Feature type

non_protein_coding_gene

FlyBase ID

FBgn0045498

Created / Updated

2003-12-01/2003-12-01

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

22B2-22B2

Sequence location

2L:1,789,141..1,790,361 [-]

Map ( GBrowse )

Summary Information

Automatically generated summary

See sections below for more information

The gene Gustatory receptor 22d is referred to in FlyBase by the symbol Gr22d (CR31930, FBgn0045498). It has the cytological map location 22B2. Its sequence location is 2L:1789141..1790361. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

22B2-22B2

Limits computationally determined from genome sequence between P{lacW}CG17646^k11021 and P{EP}EP366

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Molecular Map Data

Gene Order (in direction of increasing cytology)

References

Gene Order (overall orientation not stated)

References

Gene Model & Products

Please see the GBrowse view of Dmel\Gr22d for information on other features

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Gr22d-RA

FBtr0077900

NR_001321

1163

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Name

AE002940

Maps to

Does NOT map to

Identified with

Mapped Features & Mutations

Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

FlyBase-Curated Data

Transcript data

Please see the FlyBase Gene Expression Report for details of gene expression from the literature.

Summary of Transcript Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0045498

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

FBgn0045498

Alleles & Phenotypes

Summary of Allele Phenotypes

Phenotype manifest in

Allele

Classical Alleles ( 1 )

For All Classical Alleles Show

Allele of Gr22d	Class	Mutagen	Stocks	Known lesion
Gr22d¹		spontaneous	2	Yes

Alleles Carried on Transgenic Constructs ( 0 )

For All Alleles Carried on Transgenic Constructs Show

Allele of Gr22d	Class	Mutagen	Stocks	Known lesion

Aneuploid Aberrations

Useful deficiency

Df(2L)frtz11

Disrupted in

Df(2L)Exel7007

(Ryder, 2004.4.26)

Df(2L)Exel8005

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

Insertions

Type of insertions

Name

Expression data

Related Comments

Please look at the allele reports for the complete phenotype data

Gene Ontology: Function, Process & Cellular Component ( 0 )

Molecular Function

CV term

Evidence

References

Biological Process

CV term

Evidence

References

Cellular Component

CV term

Evidence

References

Sequence Ontology: Class of Gene

non_protein_coding_gene

nuclear_gene

Interactions & Pathways

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

Gr22d allele

Gene

References

External Data

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

534279

Orthologs

Genome-wide drosophilid orthologs

Curated drosophilid orthologs

Linkouts

Functional Complementation between Species

Inter-Species Misexpression Data

Produces phenotype in

Produces NO phenotype in

Stocks & Reagents

Stocks Listed in FlyBase ( 2 )

Tucson

14021-0231.36

y¹ oc^R3.2; Gr22b¹ Gr22d¹ cn¹ CG33964^R4.2 bw¹ sp¹; LysC¹ lab^R4.2 MstProx¹ GstD5¹ Rh6¹ <E>

Bloomington

2057

y¹ oc^R3.2; Gr22b¹ Gr22d¹ cn¹ CG33964^R4.2 bw¹ sp¹; LysC¹ lab^R4.2 MstProx¹ GstD5¹ Rh6¹ <E>

Genomic Clones ( 1 )

BACR25P15

cDNA Clones ( 0 )

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Affy Oligo

Linkouts

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0045498

Other Information

Discoverer

Etymology

Identification

Position Effect Variegation Data

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Comments About Role

Comments About Molecular Function

Gr22d may be a strain-specific young pseudogene.

(Robertson, 2003.6.24)

Other Comments

FlyBase curator comment: Stated to be a pseudogene though see FBrf0168007 for explanantion that 'pseudogene' is actually Gr22d¹.

(Dunipace et al., 2001)

New annotation (CR31930) in release 3 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NR_001321

DDBJ / EMBL / GenBank

•

Other Crossreferences

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

534279

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0045498

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0045498

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

FBgn0045498

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0045498

Synonyms & Secondary IDs ( 6 )

Reported As

Symbol Synonym

CR31930

Gr22d

Gr22dP

(Robertson, 2003.6.24)

Gr2940.2

(Scott and Axel, 2001.4.25, )

Name Synonym

Gustatory receptor 22d

(Robertson, 2001.11.11)

Gustatory receptor 2940.2

(Scott and Axel, 2001.4.25)

Secondary FlyBase IDs

FBgn0045493
FBgn0051930

References ( 9 )

Research paper

Robertson et al., 2003, Proc. Natl. Acad. Sci. USA 100(Supplement 2): 14537--14542: Molecular evolution of the insect chemoreceptor gene superfamily in Drosophila melanogaster. [FBrf0168007]
Dunipace et al., 2001, Curr. Biol. 11(11): 822--835: Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system. [FBrf0137203]

Review

Amrein and Thorne, 2005, Curr. Biol. 15(17): R673--R684: Gustatory Perception and Behavior in Drosophila melanogaster. [FBrf0187293]
Matsunami and Amrein, 2003, GenomeBiol. 4(7): 220: Taste and pheromone perception in mammals and flies. [FBrf0160781]

Personal communication to FlyBase

Ryder, 2004.4.26, Exelixis CG deletion data.: Exelixis CG deletion data. [FBrf0184335]
Robertson, 2003.6.24, FlyBase error report for CG1978 on Tue Jun 24 18:07:49 2003.: FlyBase error report for CG1978 on Tue Jun 24 18:07:49 2003. [FBrf0161500]
Robertson, 2001.11.11, Annotation revisions.: Annotation revisions. [FBrf0141780]
Scott and Axel, 2001.4.25, Gr genes.: Gr genes. [FBrf0137428]

FlyBase analysis

FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome.: Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886]