Gene Dmel\Acon

General Information
Symbol	Dmel\Acon	Species	D. melanogaster
Name	Aconitase	Annotation symbol	CG9244
Feature type	protein_coding_gene	FlyBase ID	FBgn0010100
Created / Updated	2003-12-01/2007-03-20
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	39A7-39A7	Sequence location	2L:21,168,356..21,172,897 [+]
Map ( GBrowse )
Summary Information
Automatically generated summary See sections below for more information	The gene Aconitase is referred to in FlyBase by the symbol Acon (CG9244, FBgn0010100). It has the cytological map location 39A7. Its sequence location is 2L:21168356..21172897. Its molecular function is described as: aconitate hydratase activity; 4 iron, 4 sulfur cluster binding. It is involved in the biological process tricarboxylic acid cycle. 17 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 39A7-39A7 Limits computationally determined from genome sequence between P{lacW}l(2)k07215^k07215&P{lacW}snRNA:U4:39B^k09410 and P{lacW}l(2)k14505^k14505&P{lacW}l(2)k05106^k05106
Experimentally Determined Cytological Location
Cytogenetic map Notes References 39B1-39B2 (determined by in situ hybridisation) (Spradling et al., 1999) 39A6-39A7 39B1--2 (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology) References Gene Order (overall orientation not stated) References
Gene Model & Products
Please see the GBrowse view of Dmel\Acon for information on other features
Comments on Gene Model
	EST data support existence of multiple transcripts due to variable use of 5' exons
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Acon-RB FBtr0081473 NM_079969 3029 787 Acon-RC FBtr0112855 NM_001103716 2666 683
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kD) Length (aa) Theoretical pI RefSeq ID GenBank protein Acon-PB FBpp0081002 85.4 787 8.36 NP_524708 AAF53973 Acon-PC FBpp0111768 73.6 683 7.51 NP_001097186 ABV53697
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts	PANTHER - Protein classification by function, families, and pathways • FBgn0010100
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Aconitase/3-isopropylmalate dehydratase, swivel (IPR015928) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3 (IPR015931) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 (IPR015932) Aconitase-like core (IPR015937) Aconitase A/isopropylmalate dehydratase small subunit, swivel (IPR000573) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha (IPR001030) Thiolase (IPR002155) Aconitase, mitochondrial-like (IPR006248) MitoDrome - A database of annotated Dmel nuclear genes encoding mitochondrial proteins • MTDROME09244
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA202059 AA202567 AA246943 AA698911 AA699003 AA804023 AA817339 AA820704 AA820714 AA820987 AA821225 AA941576 AA948963 AA950294 AA978409 AA990826 AE003669 AAF53973 AI062415 AI106704 AI106740 AI107047 AI107341 AI109671 AI113618 AI113976 AI114115 AI133994 AI134033 AI134048 AI135077 AI135165 AI135701 AI237936 AI238251 AI258423 AI259138 AI259718 AI259922 AI293418 AI295425 AI296845 AI386517 AI386839 AI387425 AI387872 AI389301 AI389347 AI402914 AI403311 AI404195 AI405619 AI455499 AI513774 AI517032 AI519390 AI519710 AI520461 AI532600 AI532765 AI542131 AI542670 AI542896 AI543175 AI543327 AI543684 AJ252018 CAB93521 AJ252019 CAB93522 AQ025661 AQ034137 AY051705 AAK93129 BG632558 BG633034 BG635891 BG640342 BI141905 BI162046 BI162047 BI163871 BI164456 BI164622 BI166544 BI167170 BI168847 BI169838 BI170237 BI171097 BI171313 BI172253 BI173909 BI212216 BI212592 BI213136 BI213402 BI213501 BI213804 BI215721 BI215863 BI227561 BI227593 BI228217 BI230948 BI231487 BI232388 BI235899 BI237360 BI237448 BI237950 BI238109 BI238110 BI238406 BI239257 BI239776 BI240056 BI241999 BI242818 BI353460 BI357056 BI361314 BI361440 BI362427 BI362691 BI362751 BI363338 BI364044 BI364127 BI364919 BI365726 BI366651 BI366814 BI366890 BI367733 BI368078 BI370228 BI371379 BI371811 BI373028 BI373376 BI373380 BI374862 BI376119 BI481764 BI481981 BI482926 BI483011 BI483763 BI483948 BI484085 BI484256 BI484531 BI485398 BI486104 BI563370 BI563730 BI565196 BI565346 BI566847 BI567055 BI567332 BI568615 BI569052 BI569588 BI570015 BI570180 BI570183 BI570342 BI570375 BI572096 BI572819 BI573478 BI573479 BI573606 BI573607 BI574277 BI574493 BI574755 BI574800 BI574812 BI575650 BI575826 BI576215 BI576820 BI577274 BI577453 BI577615 BI578658 BI579602 BI580366 BI580392 BI580837 BI584175 BI584364 BI584482 BI585297 BI585853 BI586360 BI586668 BI587679 BI587838 BI587892 BI589868 BI590104 BI590109 BI590164 BI590218 BI590574 BI592529 BI592928 BI593089 BI604403 BI605189 BI605261 BI605781 BI606338 BI606853 BI607259 BI607279 BI607302 BI607322 BI608069 BI609121 BI610383 BI610700 BI611424