HomeGene Dmel\for
| General Information | ||||
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| Symbol | Dmel\for | Species | D. melanogaster | |
| Name | foraging | Annotation symbol | CG10033 | |
| Feature type | protein_coding_gene | FlyBase ID | FBgn0000721 | |
| Created / Updated | 2005-01-19/2005-01-19 | |||
| Genomic Location | ||||
| Chromosome (arm) | 2L | Recombination map | 2-10 | |
| Cytogenetic map | 24A2-24A4 | Sequence location | 2L:3,622,074..3,656,951 [-] | |
| Map ( GBrowse ) | 
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Summary Information
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Automatically generated summary
See sections below for more information | The gene foraging is referred to in FlyBase by the symbol for (CG10033, FBgn0000721). It has the cytological map location 24A2-24A4. Its sequence location is 2L:3622074..3656951. Its molecular function is described as: cyclic nucleotide-dependent protein kinase activity; cGMP-dependent protein kinase activity; protein serine/threonine kinase activity; ATP binding; cAMP-dependent protein kinase regulator activity. It is involved in the biological processes: larval feeding behavior; protein amino acid phosphorylation; larval locomotory behavior; feeding behavior; regulation of heart contraction; regulation of protein amino acid phosphorylation. 54 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/larval tracheal system; crystal cell. It has 10 annotated transcripts and 10 annotated polypeptides. | |||
| External Summaries | ||||
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Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
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| Gene/Allele symbols may differ from current usage | for: foraging
The major gene responsible for foraging strategy of
feeding larvae. Larvae from so-called sitter strains move
about 6.5 cm in five minutes while feeding on a yeasted surface, whereas those from so-called rover strains travel some
17 cm; heterozygotes are rovers. Several X-ray induced reversions of the dominant rover phenotype shown to be non-complementing lethals which map to 10 on chromosome 2, thus
localizing a major behavioral locus.
Pkg2
Encodes products with putative cGMP-dependent protein kinase activities (indicated by sequencing data obtained
for all but two of the predicted proteins). The role of the
gene and its enzymes in the organism as a whole is unknown at
present.
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Detailed Mapping Data
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| FlyBase Computed Cytological Location | ||||
Cytogenetic map Evidence for location 24A2-24A4
Limits computationally determined from genome sequence between P{PZ}oddrF111&P{PZ}for06860 and P{EP}EP2595EP2595
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| Experimentally Determined Cytological Location | ||||
Cytogenetic map Notes References 24A1-24A2 (determined by in situ hybridisation)
24A1-24A2 24A3--3 24A3--4
24A-24A (determined by in situ hybridisation)
24A-24A (determined by in situ hybridisation)
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| Experimentally Determined Recombination Data | ||||
| Location | 2-10 | |||
| Left of (cM) | ||||
| Right of (cM) | ||||
| Notes | Maps adjacent to cutlet. | |||
| Molecular Map Data | ||||
Gene Order (in direction of increasing cytology)
References Gene Order (overall orientation not stated) References | ||||
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Gene Model & Products
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Please see the
GBrowse view of
Dmel\for
for information on other features
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| Comments on Gene Model | ||||
Transposon inserted in intron | ||||
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Transcript Data
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| Annotated Transcripts | ||||
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) FBtr0100363
3835
934 | ||||
| Additional Transcript Data & Comments | ||||
| Reported size (kB) | 4.6, 4.4, 3.6 (northern blot) | |||
| Comments | The existence of the "T3a" transcript is surmised from primer extension experiments. It may not be real. The "T3b" start is much more prevalent. | |||
| External Data | ||||
| Crossreferences | ||||
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Polypeptide Data
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| Annotated Polypeptides | ||||
Name FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
FBpp0099769
105.9
934
8.32
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| Additional Polypeptide Data & Comments | ||||
| Reported size (kD) | 1088, 934, 919, 894, 742, 567 (aa) | |||
| Comments | One of several protein products. Putative product of the "T3a" transcript. One of several protein products | |||
| External Data | ||||
| Linkouts | PANTHER
- Protein classification by function, families, and pathways
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| Crossreferences | InterPro
domains - A database of protein families, domains, and functional sites
• Cyclic nucleotide-binding (IPR000595)
Protein kinase, core (IPR000719)
Protein kinase, C-terminal (IPR000961)
Serine/threonine protein kinase (IPR002290)
cAMP/cGMP-dependent protein kinase (IPR002373)
cGMP-dependent protein kinase, core (IPR002374)
Serine/threonine protein kinase, active site (IPR008271)
Protein kinase-like (IPR011009)
RmlC-like jelly roll fold (IPR014710)
Protein kinase ATP binding, conserved site (IPR017441)
Serine/threonine protein kinase-related (IPR017442)
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Sequences Consistent with the Gene Model
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| DDBJ
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EMBL / GenBank | DNA sequence Protein sequence Name | |||