Allele Dmel\B¹

General Information
Symbol	Dmel\B¹	Species	D. melanogaster
Name		FlyBase ID	FBal0000817
Feature type	allele	Created / Updated	2006-08-22/2006-08-22
Associated gene	Dmel\B

Allele class
Mutagen	spontaneous
Nature of the Allele
Allele class
Mutagen	spontaneous
Mapped Features and Mutations
Type Symbol & Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Insertion of a roo-element at cytological location 16A7-16A1. (Tsubota, 1991)
Assay mode
Caused by aberration	Dp(1;1)B (Sutton, 1943, Tsubota, 1991, Epps et al., 1997)
Carried on aberration	FM7c-vHa (FlyBase Curators, 2006-) FM7f-P{ftz-lac} (FlyBase Curators, 2006-) FM7c-FTG (FlyBase Curators, 2006-) FM7c-actLacZ (FlyBase Curators, 2006-) FM7h-N^Placr (FlyBase Curators, 2006-, Heitzler, 1997) FM7c-vKa (FlyBase Curators, 2006-) FM6^T8LZ (FlyBase Curators, 2006-) FM7c-10 (FlyBase Curators, 2006-) FM7c-34 (FlyBase Curators, 2006-) FM6-vFa (FlyBase Curators, 2006-) Binsc-3AWS (FlyBase Curators, 2006-) FM6l (FlyBase Curators, 2006-) FM6-l(1)FMa (FlyBase Curators, 2006-) Biny (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 1998.5.16) FM7a (FlyBase Curators, 2006-, Merriam, 1968, Lindsley and Zimm, 1992) FM6-w¹ (FlyBase Curators, 2006-) FM6v^ESB (FlyBase Curators, 2006-) FM6 (FlyBase Curators, 2006-, Lindsley and Zimm, 1992) FM7a-m73 (FlyBase Curators, 2006-) FM7g-N^nd-0 (FlyBase Curators, 2006-) FM7k (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 1998.5.21) Binsc (FlyBase Curators, 2006-, Lindsley and Zimm, 1992) FM3-v^Of (FlyBase Curators, 2006-) FM4 (FlyBase Curators, 2006-, Lindsley and Zimm, 1992) Bascy (FlyBase Curators, 2006-, Lindsley and Zimm, 1992, Bloomington Drosophila Stock Center, 1998.5.16) FM4-vMa FM6-wc (FlyBase Curators, 2006-) FM7d (FlyBase Curators, 2006-) Binscy (FlyBase Curators, 2006-, Lindsley and Zimm, 1992) Binsn (FlyBase Curators, 2006-, Lindsley and Zimm, 1992) Binscop (FlyBase Curators, 2006-, Green, 2005.2.15) FM7g-ct^ns (FlyBase Curators, 2006-) FM6-wⁱdm⁺ (FlyBase Curators, 2006-) FM1-lz⁺ (FlyBase Curators, 2006-) FM7c-ct^S (FlyBase Curators, 2006-) FM3 (FlyBase Curators, 2006-, Lindsley and Zimm, 1992) FM7i (FlyBase Curators, 2006-, Heitzler, 1997) FM6-vAb (FlyBase Curators, 2006-) FM4-vAb (FlyBase Curators, 2006-) FM7a-nod⁴ (FlyBase Curators, 2006-) FM7f (FlyBase Curators, 2006-, Heitzler, 1997) FM7j-B¹ (FlyBase Curators, 2006-, Roote, 2001.12.11) FM1 (FlyBase Curators, 2006-, Lindsley and Zimm, 1992, Bloomington Drosophila Stock Center, 1998.5.16) FM7e (FlyBase Curators, 2006-) FM7i-pAct-GFP (FlyBase Curators, 2006-, Reichhart and Ferrandon, 1998.6.8, Reichhart and Ferrandon, 1998) FM7c (FlyBase Curators, 2006-) Basc (FlyBase Curators, 2006-, Lindsley and Zimm, 1992, Bloomington Drosophila Stock Center, 1998.5.16) FM7c-sn⁺ (FlyBase Curators, 2006-) Bwinscy (FlyBase Curators, 2006-, Sekelsky et al., 1999) FM0 (FlyBase Curators, 2006-, Lindsley and Zimm, 1992, Bloomington Drosophila Stock Center, 1998.5.16) FM7w (FlyBase Curators, 2006-) FM6-12 (FlyBase Curators, 2006-) In(1)sc^8Lsc^S1R+dl-49 FM7h (FlyBase Curators, 2006-) FM4-vAa (FlyBase Curators, 2006-) ClB (FlyBase Curators, 2006-, Lindsley and Zimm, 1992) FM7-l(1)TW24¹ (FlyBase Curators, 2006-) Binsinscy (FlyBase Curators, 2006-, Lindsley and Zimm, 1992) FM6K (FlyBase Curators, 2006-) FM7c-w⁺ (FlyBase Curators, 2006-) FM7b (FlyBase Curators, 2006-) FM7a-l (FlyBase Curators, 2006-) FM6-vAa (FlyBase Curators, 2006-) FM6-ct^83h (FlyBase Curators, 2006-) FM7g (FlyBase Curators, 2006-, Heitzler, 1997)
Cytology
Phenotypic Data
Phenotypic Class
	viable (Lindsley and Zimm, 1992) visible (Steinberg, 1937, Lindsley and Zimm, 1992) visible \| dominant (Brennan et al., 2001)
Phenotype Manifest In
	eye (Hiebert and Birchler, 1994, Sedkov et al., 2003, Brennan et al., 2001, Lindsley and Zimm, 1992) ommatidium (Steinberg, 1937, Lindsley and Zimm, 1992)
Detailed Description
	Statement Reference RK1A. Dana\B-H1 sequences hybridized to the duplicated regions of B¹, B², B^MR2 and B^MR3. (Tanda and Corces, 1991) Eye restricted to narrow vertical bar. Homozygous female fully viable. B¹/+ female has about 360 facets and shows indentation terminating in horizontal fissure on anterior margin of eye, producing a kidney-shaped eye. B¹/B¹ and B¹/+ completely separable from wild type; in some genetic backgrounds, B¹/B¹ overlaps B¹/+ slightly. Classifiable in single dose in triploids by slight anterior nick in eye; is useful in the recognition of triploids. (Lindsley and Zimm, 1992) B¹ males that are also mutant at mle⁴ males have narrower eyes than their mle⁴/+ sibs. (Hiebert and Birchler, 1994) All three pairs of legs are wild type in mutant flies. The antennae are normal. (Mandal and Lakhotia, 1999) Heterozygotes have a deep anterior nick in the adult eye. (Brennan et al., 2001)
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement Reference B¹ has visible \| dominant phenotype, enhanceable by br⁵/br[+] (Brennan et al., 2001) B¹ has visible \| dominant phenotype, enhanceable by br^npr-3/br[+] (Brennan et al., 2001)
Suppressed by
Statement Reference B¹ has visible phenotype, suppressible by su(B)¹ (Steinberg, 1937) B¹ has visible \| dominant phenotype, suppressible by br[+]/br^2Bc-1 (Brennan et al., 2001) B¹ has visible \| dominant phenotype, suppressible by br^rbp-5/br[+] (Brennan et al., 2001)
Enhancer of
Statement Reference B¹ is an enhancer of visible phenotype of dpp^d6/dpp^d12 (Mandal and Lakhotia, 1999) B[+]/B¹ is an enhancer of visible \| dominant phenotype of L² (Singh et al., 2005) B¹ is an enhancer of visible phenotype of H^Scer\UAS.cMa, Scer\GAL4^GMR.PF (Mueller et al., 2005)
Phenotype Manifest In
Enhanced by
Statement Reference B¹, ecd¹ has eye phenotype, enhanceable by trr¹ (Sedkov et al., 2003) B¹ has phenotype, enhanceable by Bg² B¹ has eye phenotype, enhanceable by oro¹/oro[+] (Epps et al., 1997) B¹ has eye phenotype, enhanceable by oro²/oro[+] (Epps et al., 1997) B¹ has eye phenotype, enhanceable by br⁵/br[+] (Brennan et al., 2001) B¹ has eye phenotype, enhanceable by br^npr-3/br[+] (Brennan et al., 2001)
Suppressed by
Statement Reference B¹ has ommatidium phenotype, suppressible by su(B)¹ (Steinberg, 1937) B¹ has eye phenotype, suppressible by trr^+t12 (Sedkov et al., 2003) B¹ has phenotype, suppressible \| partially by su(Hw)² (Lindsley and Grell, 1968) B¹ has eye phenotype, suppressible by br[+]/br^2Bc-1 (Brennan et al., 2001) B¹ has eye phenotype, suppressible by br^rbp-5/br[+] (Brennan et al., 2001) B¹ has phenotype, suppressible by mb¹ (Bonnier, 1934)
Enhancer of
Statement Reference B¹ is an enhancer of antenna phenotype of dpp^d6/dpp^d12 (Mandal and Lakhotia, 1999) B¹ is an enhancer of antennal segment 4 phenotype of dpp^d6/dpp^d12 (Mandal and Lakhotia, 1999) B¹ is an enhancer of antennal segment 5 phenotype of dpp^d6/dpp^d12 (Mandal and Lakhotia, 1999) B¹ is an enhancer of arista phenotype of dpp^d6/dpp^d12 (Mandal and Lakhotia, 1999) B¹ is an enhancer of femur phenotype of dpp^d6/dpp^d12 (Mandal and Lakhotia, 1999) B¹ is an enhancer of leg phenotype of dpp^d6/dpp^d12 (Mandal and Lakhotia, 1999) B¹ is an enhancer of male genitalia phenotype of dpp^d6/dpp^d12 (Mandal and Lakhotia, 1999) B¹ is an enhancer of ommatidium phenotype of dpp^d6/dpp^d12 (Mandal and Lakhotia, 1999) B¹ is an enhancer of sex comb \| supernumerary phenotype of dpp^d6/dpp^d12 (Mandal and Lakhotia, 1999) B¹ is an enhancer of tarsal segment phenotype of dpp^d6/dpp^d12 (Mandal and Lakhotia, 1999) B¹ is an enhancer of tibia phenotype of dpp^d6/dpp^d12 (Mandal and Lakhotia, 1999) B[+]/B¹ is an enhancer of eye phenotype of dpp^d-blk (Sedkov et al., 2003) B[+]/B¹ is an enhancer of eye phenotype of L² (Singh et al., 2005) B¹ is an enhancer of eye phenotype of H^Scer\UAS.cMa, Scer\GAL4^GMR.PF (Mueller et al., 2005) B¹ is an enhancer of phenotype of Bg²
Other
Statement Reference B¹, dpp^d6/dpp^d12 has antennal segment 2 sensillum phenotype (Mandal and Lakhotia, 1999, Mandal and Lakhotia, 1999) B¹, dpp^d6/dpp^d12 has antennal segment 2 phenotype (Mandal and Lakhotia, 1999, Mandal and Lakhotia, 1999) B¹, dpp^d6/dpp^d12 has antennal segment 3 sensillum phenotype (Mandal and Lakhotia, 1999, Mandal and Lakhotia, 1999) B¹, dpp^d6/dpp^d12 has antennal segment 3 phenotype (Mandal and Lakhotia, 1999, Mandal and Lakhotia, 1999) B¹, dpp^d6/dpp^d12 has leg sensillum phenotype (Mandal and Lakhotia, 1999, Mandal and Lakhotia, 1999) B¹, Pub¹ has eye phenotype (Lindsley and Zimm, 1992, Lindsley and Zimm, 1992) B¹, Pub¹ has ommatidium phenotype (Lindsley and Zimm, 1992, Lindsley and Zimm, 1992) B¹, ecd¹ has eye phenotype (Sedkov et al., 2003)
Additional Comments
Genetic Interactions
Statement Reference mb¹ is a recessive suppressor of B¹; it modifies B¹/B¹ females to a phenotype resembling or less severe than B¹/+ and modifies B¹/+ females to almost resemble wild type. B¹ males are modified to a phenotype resembling or less severe than Bⁱ. (Bonnier, 1934) su(B)¹ is a recessive modifier of B¹; it causes a great increase in the number of facets in the eyes of B¹ males, and a slight increase in the number of facets in the eyes of homozygous B¹ females. (Steinberg, 1937) Interacts with B¹ to give small, glazed, almost facetless eyes. (Lindsley and Zimm, 1992) The B¹ eye phenotype is dominantly enhanced by oro¹ and oro². The eyes of oro¹/+ ; B¹/+ flies are approximately half the size of those of B¹/+ flies. (Epps et al., 1997) The severity of the leg defects seen in dpp^d6/dpp^d16 flies is enhanced by B¹. There is an overall shortening in length along the proximal-distal axis of the leg and complete or partial fusion or even total loss of tarsal segments. The tibia and femur are deformed, showing shortening, bulging and disorganised bristle patterns. The coxa and trochanter are not so strongly affected. The sex comb of the prothoracic leg, when present, is always duplicated in these flies. The antenna phenotype of dpp^d6/dpp^d16 flies is enhanced by B¹; the arista, 4th and 5th segments are completely absent and the 2nd and 3rd segments are widened and deformed and have defects in the bristle pattern. B¹ ; dpp^d6/dpp^d16 flies completely lack ommatidia. All B¹ ; dpp^d6/dpp^d16 males completely lack external genitalia. (Mandal and Lakhotia, 1999) In animals that are homozygous for ecd¹ and are also B¹ the addition of trr¹ enhances the eye phenotype. (Sedkov et al., 2003) B¹/+ ; L²/+ animals have a no eye phenotype. (Singh et al., 2005)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 119 )
Bloomington	2969 B¹ 4295 R(Y)F(9)/B¹ 4296 R(Y)F(H2)/B¹ 3972 Bg¹ B¹/In(1)AM 727 Df(1)g, f¹ B¹/In(1)AM 1504 B¹ P{neoFRT}18A; ry⁵⁰⁶ 2839 f¹ B¹/C(1)DX, y¹ f¹
Kyoto	107498 B¹ 108777 FM7j, B¹ 108910 Df(1)g, f¹ B¹/In(1)AM 108381 Basc, Df(1)BA2-8, w^a B¹/FM7c 103238 Basc, sc⁸ sc^S1 w^a B¹
	More stocks available...
Notes on Origin
Discoverer	Tice.
	Selected as: Female.
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	B (Mandal and Lakhotia, 1999, Steinberg, 1937) B¹
Name Synonym
Secondary FlyBase IDs

References ( 25 )

Generate a list of	All references relating to this allele ( 25 )

List References by type	Research paper ( 15 ) Supplementary material ( 1 ) Personal communication to FlyBase ( 5 ) FlyBase analysis ( 1 ) Letter ( 1 ) Book ( 2 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2006 Show research papers ...

Allele Dmel\B1

Allele Dmel\B¹