Aberration Dmel\Df(4)ED6364

General Information
Symbol	Dmel\Df(4)ED6364	Species	D. melanogaster
Name		FlyBase ID	FBab0037588
Feature type	chromosomal_deletion	Created / Updated	2006-08-22/2006-08-22

Formalized genetic data
Sequence coordinates	4:79870..214111 (101F1;102A6)
Deleted segment	102A3--102B1
Duplicated segment
Computed Breakpoints include	102A3
Breakpoints Inherited
Nature of the Aberration
Cytological Order
Progenitor	P{RS3r}CB-0038-3 (Ryder, 2003.6.17, Ryder et al., 2004, Ryder and Roote, 2004.11.10) P{RS5r}CG2316^5-HA-1572r (Ryder, 2003.6.17, Ryder et al., 2004, Ryder and Roote, 2004.11.10)
Mutagen	FLPase (Ryder, 2003.6.17, Ryder et al., 2004, Ryder and Roote, 2004.11.10)
Class of aberration (relative to progenitor)	chromosomal_deletion (Ryder, 2003.6.17, Ryder et al., 2004, Ryder and Roote, 2004.11.10)
Breakpoints
Causes alleles	CG2316^ED6364 (Ryder et al., 2004)
Carries alleles
Transposon Insertions	P{3'.RS5+3.3'}CG2316^ED6364 (Ryder and Roote, 2004.11.10, Ryder et al., 2004, Ryder, 2003.6.17)
Genetic mapping information
Comments
Comments on Cytology
	Limits computationally determined from location of progenitor P insertion on genome sequence between P{SUPor-P}KG01127&PBac{5HPw⁺}A173 and PBac{5HPw⁺}A437 Confirmed by 3-step PCR confirmation as shown in http://www.drosdel.org.uk/del_confirm.php Confirmed by lack of complementation to a known lethal mutation predicted to fall between the progenitor insertions. (Ryder and Roote, 2005.11.4) Confirmed by PCR (using the 3-step process described on http://www.drosdel.org.uk/del_confirm.php). (Ryder and Roote, 2004.11.10)
Molecularly Mapped Breakpoints

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	RpS3A (Ryder and Roote, 2004.11.10) gvl (Ryder and Roote, 2004.11.10) pan (Roote, 2004.6.24, Ryder et al., 2004, Ryder and Roote, 2004.11.10)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	bt (Ryder and Roote, 2004.11.10)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Shows a Minute phenotype: this chromosome predicted to delete RpS3A. (Roote, 2004.6.24) Df(4)ED6364 does not uncover hybrid sterility when heterozygous in males containing the D.simulans 4th chromosome introgressed into an otherwise D.melanogaster background. (Masly et al., 2006)
Position Effect Variegation Data

Stocks ( 1 )
Bloomington	9421 w¹¹¹⁸; Df(4)ED6364, P{3\'.RS5+3.3\'}CG2316^ED6364/l(4)102EFf¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Df(4)ED6364 (Masly et al., 2006)
Name Synonym
Secondary FlyBase IDs

References ( 7 )
Research paper	Masly et al., 2006, Science 313(5792): 1448--1450 Gene transposition as a cause of hybrid sterility in Drosophila. [FBrf0192921] Ryder et al., 2004, Genetics 167(2): 797--813 The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster. [FBrf0179424]
Personal communication to FlyBase	Ryder and Roote, 2005.11.4, Update from DrosDel Database - Release 4 mappings - November 2005. Update from DrosDel Database - Release 4 mappings - November 2005. [FBrf0188738] Roote, 2004.6.24, ED genetic data. ED genetic data. [FBrf0178881] Ryder and Roote, 2004.11.10, DrosDel deletions confirmed by PCR and genetic tests. DrosDel deletions confirmed by PCR and genetic tests. [FBrf0179888] Ryder, 2003.6.17, Drosdel deletions. Drosdel deletions. [FBrf0161091]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]