A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Aberration Dmel\Df(2L)H20

General Information
SymbolDmel\Df(2L)H20SpeciesD. melanogaster
NameFlyBase IDFBab0001470
Feature typechromosomal_deletionCreated / Updated2006-08-22/2006-08-22
Formalized genetic data her << bk1 << l(2)k04206 << bk2 << Dox-A3
Sequence coordinates
Deleted segment36A8--36F1
Duplicated segment
Computed Breakpoints include 36A8-36A9;36F1
Breakpoints Inherited  
hide Nature of the Aberration
Cytological Order
Progenitor
Mutagen
X ray
(Steward and Nusslein-Volhard, 1986, Simpson, 1983)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Steward and Nusslein-Volhard, 1986, Simpson, 1983, Pultz et al., 1994, Pauli et al., 1995, Homyk and Emerson, 1988, Duffy et al., 1996, Fitzpatrick et al., 1995, Harbecke and Lengyel, 1995, Landecker et al., 1994, Whalen and Wilson, 1986)
Breakpoints
36A12-36A14;36E1-36E2
(Simpson, 1983)
36A6-36A10;36E3-36F2
(Steward and Nusslein-Volhard, 1986)
36A8-36A9;36E3-36E4
(Whalen and Wilson, 1986, Landecker et al., 1994, Fitzpatrick et al., 1995)
36A6-36A7;36F1-36F2
(Homyk and Emerson, 1988)
36A8-36A9;36E1-36E2
(Schupbach and Wieschaus, 1989, Pauli et al., 1995, Harbecke and Lengyel, 1995, Duffy et al., 1996)
36A6-36A11;36E3-36F2
(Pultz et al., 1994)
Causes alleles
Fas3H20
(Marygold, 2005.1.19)
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
hide Comments on Cytology
Limits of break 1 from polytene analysis (FBrf0044474) Left limit of break 2 from polytene analysis (FBrf0048188) Right limit of break 2 from polytene analysis (FBrf0044468)
 
Ref: Ashburner et al., 1990, Genetics 126: 679--694
(Pultz et al., 1994)
Ref: FBrf0045239.
(Homyk and Emerson, 1988)
hide Molecularly Mapped Breakpoints
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
mdy
(Schupbach and Wieschaus, 1991)
Cas
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
glu
(BDGP Project Members, 1994-1999, Kania et al., 1995, Spradling et al., 1999)
qua
(Steward and Nusslein-Volhard, 1986, Schupbach and Wieschaus, 1991)
Aac11
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
BicD
(Steward and Nusslein-Volhard, 1986, Schupbach and Wieschaus, 1991)
dl
(Steward and Nusslein-Volhard, 1986, Schupbach and Wieschaus, 1989, Schupbach and Wieschaus, 1991)
ninaD
(Steward and Nusslein-Volhard, 1986)
kel
(Steward and Nusslein-Volhard, 1986, Schupbach and Wieschaus, 1991)
grp
(Li and Baker, 1998, Spradling et al., 1999)
CadN
(Steward and Nusslein-Volhard, 1986, Brumby et al., 2004)
l(2)k15102
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
l(2)k13905
(BDGP Project Members, 1994-1999, Spradling et al., 1999)
bst
(Boquet et al., 2000)
l(2)36Aa
(Steward and Nusslein-Volhard, 1986, Ashburner et al., 1990)
AcpC
(Whalen and Wilson, 1986)
ifm(2)RU2
(Nongthomba and Ramachandra, 1999)
l(2)36Ac
(Steward and Nusslein-Volhard, 1986, Ashburner et al., 1990)
l(2)36Ca
(Steward and Nusslein-Volhard, 1986)
Ifm(2)RU1
(Nongthomba and Ramachandra, 1999)
l(2)36Bb
(Steward and Nusslein-Volhard, 1986)
l(2)36Bc
(Steward and Nusslein-Volhard, 1986)
l(2)36Bd
(Steward and Nusslein-Volhard, 1986)
E(var)36AE
(Wustmann et al., 1989)
l(2)36Ab
(Steward and Nusslein-Volhard, 1986, Ashburner et al., 1990)
Ptp36E
(Fitzpatrick et al., 1995)
plo
(Steward and Nusslein-Volhard, 1986, Ashburner et al., 1990)
l(2)36Ad
(Steward and Nusslein-Volhard, 1986, Ashburner et al., 1990)
l(2)36Ba
(Steward and Nusslein-Volhard, 1986)
l(2)k04206
(Roote, 1998.11.16)
fs(2)ltoHC44
(Schupbach and Wieschaus, 1991)
Mhc
(Steward and Nusslein-Volhard, 1986, Homyk and Emerson, 1988, BDGP Project Members, 1994-1999, Cripps et al., 1994, Kronert et al., 1999, Spradling et al., 1999, Nongthomba et al., 2003, Montana and Littleton, 2004)
Cyt-c-d
(Castrillon et al., 1993)
rdo
(Steward and Nusslein-Volhard, 1986)
Molecular Data
Completely deleted
Acp36DE
(Marygold, 2005.1.19)
Partially deleted
Fas3
(Marygold, 2005.1.19)
hide Genes NOT Deleted / Disrupted
Complementation Data
Dox-A3
(Wright, 1987)
Su(H)
(Ashburner et al., 1990)
vas
(Ashburner et al., 1990)
stc
(Ashburner et al., 1990)
TfIIS
(Ashburner et al., 1990)
ck
(Ashburner et al., 1990)
esg
(Ashburner et al., 1990)
sna
(Ashburner et al., 1990)
wor
(Ashburner et al., 1990)
gft
(Ashburner et al., 1990)
l(2)35Df
(Ashburner et al., 1990)
wek
(Ashburner et al., 1990)
Gli
(Ashburner et al., 1990)
l(2)35Di
(Ashburner et al., 1990)
BicC
(Ashburner et al., 1990)
Cyp303a1
(Ashburner et al., 1990)
Syx5
(Ashburner et al., 1990)
fzy
(Ashburner et al., 1990)
chif
(Ashburner et al., 1990)
mRpL4
(Ashburner et al., 1990)
cact
(Tearle and Nusslein-Volhard, 1987, Ashburner et al., 1990)
cni
(Ashburner et al., 1990)
heix
(Ashburner et al., 1990)
crp
(Ashburner et al., 1990)
her
(Pultz et al., 1994, Li and Baker, 1998)
RpS26
(BDGP Project Members, 1994-1999, Spradling et al., 1999, Marygold, 2005.1.19)
Ca-α1D
(Ashburner et al., 1990)
CycE
(Ashburner et al., 1990)
dac
(Ashburner et al., 1990)
lace
(Ashburner et al., 1990)
l(2)k16215
(BDGP Project Members, 1994-1999)
l(2)k09927
(BDGP Project Members, 1994-1999)
l(2)35De
(Ashburner et al., 1990)
rd
(Ashburner et al., 1990)
ms(2)35Eb
(Ashburner et al., 1990)
l(2)k17039
(BDGP Project Members, 1994-1999)
l(2)35Cc
(Ashburner et al., 1990)
l(2)k10816
(BDGP Project Members, 1994-1999)
l(2)k07020
(BDGP Project Members, 1994-1999)
ncm
(Marygold, 2005.1.19, Coelho et al., 2005)
bun
(BDGP Project Members, 1994-1999)
Molecular Data
CG31749
(Marygold, 2005.1.19)
CG10176
(Marygold, 2005.1.19)
CG10178
(Marygold, 2005.1.19)
CG10211
(Marygold, 2005.1.19)
kon
(Marygold, 2005.1.19)
CG10283
(Marygold, 2005.1.19)
bsf
(Marygold, 2005.1.19)
RpS26
(Marygold, 2005.1.19)
Pde11
(Marygold, 2005.1.19)
ncm
(Marygold, 2005.1.19)
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
hide Related Comments
hide Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Df(2L)H20 in combination with a pair of introgressions from D.simulans spanning 30F1-31E7 to 35D7-36A14 Dsim\Int(2L)S and 21A1 to 22D1--23A2 Dsim\Int(2L)D produces sterile male flies. These flies are female sterile.
(Sawamura et al., 2000)
Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.
(Coyne et al., 1998)
Dominantly causes tergite defects in less than 50% of run3 heterozygotes.
(Duffy et al., 1996)
Heterozygosity for Df(2L)H20 results in 2.8% X chromosome nondisjunction and 0.0% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.
(Harris et al., 2003)
Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.
(Pauli et al., 1995)
Heterozygotes are flightless, but show normal muscle patterns, except for a reduced birefringence of the indirect flight muscles compared to those of wild type.
(Nongthomba and Ramachandra, 1999)
Heterozygotes show no adult central brain defect.
(Boquet et al., 2000)
Homozygous embryos have a truncated head and the stomodeum is shifted anteriorly.
(Harbecke and Lengyel, 1995)
Intermediate second site non-complementing phenotype with zipEbr and zipmhc-c6.1: malformed phenotype penetrance 25-75%.
(Halsell and Kiehart, 1998)
Midgut development of mutant embryos is wild type.
(Bilder and Scott, 1995)
Nonmotile germ cells.
(Warrior, 1994)
Shows no maternal enhancement of dpphr4.
(Nicholls and Gelbart, 1998)
The Df(2L)H20 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3\'WP-2,wvar}2Lt insertion).
(Mason et al., 2004)
Lysates from 4 hour old prepupae heterozygous for Df(2L)H20 show no reduction in caspase activation compared to wild type.
(Dorstyn et al., 2004)
hide Position Effect Variegation Data
  
hide Stocks ( 3 )
Bloomington
3180
Df(2L)H20, b1 pr1 cn1 sca1/CyO
Kyoto
106898
Df(2L)H20, b1 pr1 cn1 sca1/CyO
103256
CyO, Cy1 dplv1 pr1 cn2 / Df(2L)H20, b1 pr1 cn1 sca1
hide Notes on Origin
Discoverer
Nusslein-Volhard.
 
C. Nusslein-Volhard.
(Simpson, 1983)
hide Balancer / Genotype Variants of the Aberration
    hide Separable Components
      hide Other Comments
      hide Synonyms & Secondary IDs ( 10 )
      Reported As
      Symbol Synonym
      Df(2)H20
      (Nongthomba et al., 2003, Kronert et al., 1999)
      Df(2L)dl2034
       
      Df(2L)dlH20
      (Simpson, 1983)
      Df(2L)dl-H20
       
      Df(2L)H2
      (Duffy et al., 1996, Bilder and Scott, 1995)
      Df(2L)H20
      (Jordan et al., 2006, Marygold, 2005.1.19, Dorstyn et al., 2004, Crest et al., 2007)
      Df(2L) H20
      (Dorstyn et al., 2004)
      Df(2L)H20(d12034)
      (Harris et al., 2003)
      Df(2L)H2O
      (Chapman et al., 2000)
      Df(Δdc3/dc4)
      (Dorstyn et al., 2004)
      Name Synonym
      Secondary FlyBase IDs
        hide References ( 66 )
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        hide Recent research papers ( 2 )
        Crest et al., 2007, Genetics 175(2): 567--584
        Onset of the DNA replication checkpoint in the early Drosophila embryo. [FBrf0194644]
        Jordan et al., 2006, Genetics 174(1): 271--284
        Quantitative trait loci for locomotor behavior in Drosophila melanogaster. [FBrf0193517]
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