Aberration Dmel\Df(2L)A48

General Information
Symbol	Dmel\Df(2L)A48	Species	D. melanogaster
Name	Deficiency (2L) Aaron	FlyBase ID	FBab0001416
Feature type	chromosomal_deletion	Created / Updated	2006-08-22/2006-08-22

Formalized genetic data	noc << bk1 << Adh << lace << bk2 << CycE
Sequence coordinates
Deleted segment	35B2--35D5
Duplicated segment
Computed Breakpoints include	35B2;35D5
Breakpoints Inherited
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray (McNabb et al., 1996, Fossett et al., 1994, Grau et al., 1984)
Class of aberration (relative to progenitor)	chromosomal_deletion (Gubb et al., 1990, Ashburner et al., 1982, Ashburner et al., 1983, Duffy et al., 1996, McNabb et al., 1996, Rodriguez et al., 1996, Roote et al., 1996, Gubb et al., 1984, Gubb et al., 1985, Grau et al., 1984, Tinker et al., 1998)
Breakpoints	35B3;35D5-35D7 (Ashburner et al., 1982, Grau et al., 1984) 35B1-35B2;35D5-35D7 (Ashburner et al., 1983, Gubb et al., 1985) 35B2-35B3;35D5-35D7 (Gubb et al., 1984, Duffy et al., 1996, McNabb et al., 1996, Rodriguez et al., 1996, Roote et al., 1996) 35B2;35D5-35D7 (Tinker et al., 1998)
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments	Breakpoint(s) molecularly mapped (Chia et al., 1985)
Comments on Cytology
	Left limit of break 1 from polytene analysis (FBrf0040529) Right limit of break 1 from inclusion of Adh (FBrf0038047) Left limit of break 2 from polytene analysis (FBrf0038047) Right limit of break 2 from non-inclusion of CycE (FBrf0038047) Ref: FBrf0038050. (Grau et al., 1984)
Molecularly Mapped Breakpoints

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	dyn-p25 (Ashburner et al., 1982) l(2)35Bd (Ashburner et al., 1982, BDGP Project Members, 1994-1999, Spradling et al., 1999) Su(H) (Ashburner et al., 1982, Grau et al., 1984, BDGP Project Members, 1994-1999, Spradling et al., 1999) vas (Tinker et al., 1998, Cai et al., 2001) CG15269 (BDGP Project Members, 1994-1999) stc (Ashburner et al., 1982, Ashburner et al., 1982, Grau et al., 1984, Fossett et al., 1994, Spradling et al., 1999, Cai et al., 2001) vig (Cai et al., 2001) TfIIS (Fossett et al., 1994, Cai et al., 2001) ck (Ashburner et al., 1982, Ashburner et al., 1982, Grau et al., 1984, BDGP Project Members, 1994-1999, Fossett et al., 1994, Spradling et al., 1999, Cai et al., 2001) l(2)35Bg (Ashburner et al., 1982, Ashburner et al., 1982, BDGP Project Members, 1994-1999, Spradling et al., 1999) esg (BDGP Project Members, 1994-1999, Fossett et al., 1994, Rodriguez et al., 1996, Tanaka-Matakatsu et al., 1996, Spradling et al., 1999, Cai et al., 2001) sna (Ashburner et al., 1982, Ashburner et al., 1982, Grau et al., 1984, Fossett et al., 1994, Cai et al., 2001) wor (Ashburner et al., 1982, Ashburner et al., 1982, Grau et al., 1984, Fossett et al., 1994, Cai et al., 2001) gft (Ashburner et al., 1982, Ashburner et al., 1982, BDGP Project Members, 1994-1999, Fossett et al., 1994, Spradling et al., 1999, Cai et al., 2001) BicC (Grau et al., 1984) osp (Ashburner et al., 1982, Ashburner et al., 1982, Gubb et al., 1990, Grau et al., 1984, Fossett et al., 1994, McNabb et al., 1996, Roote et al., 1996, Ashraf et al., 1999) lace (Ashburner et al., 1982, Ashburner et al., 1982, Grau et al., 1984, BDGP Project Members, 1994-1999, Fossett et al., 1994, Roote et al., 1996) Adh (Ashburner et al., 1982, Ashburner et al., 1982, Gubb et al., 1990, Grau et al., 1984, Fossett et al., 1994, McNabb et al., 1996, Roote et al., 1996, Roote, 2002.1.15) l(2)35Bc (Ashburner et al., 1982, Gubb et al., 1990) rd (Ashburner et al., 1982, Ashburner et al., 1982, Grau et al., 1984) l(2)35Cc (Fossett et al., 1994, Cai et al., 2001) l(2)35Ch (Cai et al., 2001) l(2)35Be (Ashburner et al., 1982) l(2)35Cg (Cai et al., 2001) mol (Ashburner et al., 1982, Ashburner et al., 1982, Gubb et al., 1990, Grau et al., 1984, Fossett et al., 1994, McNabb et al., 1996, Roote et al., 1996)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Sos (Ashburner et al., 1982, Gubb et al., 1990) Orc5 (Gubb et al., 1990) RpII33 (Ashburner et al., 1982, Gubb et al., 1990, Fossett et al., 1994) Ance (Ashburner et al., 1982, Gubb et al., 1990, Fossett et al., 1994) Sop2 (Ashburner et al., 1982, Gubb et al., 1990) tam (Ashburner et al., 1982, Gubb et al., 1990) l(2)34Fa (Ashburner et al., 1982, Gubb et al., 1990, Fossett et al., 1994) rk (Ashburner et al., 1982, Gubb et al., 1990, Fossett et al., 1994, Eriksen et al., 2000) wb (Ashburner et al., 1982, Gubb et al., 1990, Fossett et al., 1994) Pgant35A (Ashburner et al., 1982, Ashburner et al., 1982, Gubb et al., 1990, Fossett et al., 1994, Roote et al., 1996) elB (Grau et al., 1984, BDGP Project Members, 1994-1999, Fossett et al., 1994, Roote et al., 1996) noc (Ashburner et al., 1982, Ashburner et al., 1982, Gubb et al., 1990, Grau et al., 1984, Fossett et al., 1994, McNabb et al., 1996, Roote et al., 1996) vas (BDGP Project Members, 1994-1999) l(2)35Df (BDGP Project Members, 1994-1999) wek (BDGP Project Members, 1994-1999, Fossett et al., 1994) mRpL4 (Fossett et al., 1994) osp (BDGP Project Members, 1994-1999, Spradling et al., 1999) Ca-α1D (Fossett et al., 1994) CycE (Ashburner et al., 1982, Ashburner et al., 1982, Grau et al., 1984, BDGP Project Members, 1994-1999, Fossett et al., 1994) kuz (Fossett et al., 1994) DNApol-γ35 (Ashburner et al., 1982, Gubb et al., 1990) b (Ashburner et al., 1982, Gubb et al., 1990) l(2)k05614 (BDGP Project Members, 1994-1999) l(2)34Fd (Ashburner et al., 1982, Gubb et al., 1990, Roote et al., 1996) elA (Ashburner et al., 1982, Ashburner et al., 1982, Gubb et al., 1990, Grau et al., 1984, Fossett et al., 1994, Roote et al., 1996) l(2)35De (Fossett et al., 1994) l(2)k09033 (BDGP Project Members, 1994-1999) j (Ashburner et al., 1982, Gubb et al., 1990) l(2)34Fc (Ashburner et al., 1982, Ashburner et al., 1982, Gubb et al., 1990, Fossett et al., 1994, Roote et al., 1996) l(2)k09208 (BDGP Project Members, 1994-1999) l(2)k09017a (BDGP Project Members, 1994-1999) l(2)34Db (Ashburner et al., 1982, Fossett et al., 1994) fs(2)lto1 (Roote, 1997.12.2, Ashburner et al., 1999.10.12) pu (Ashburner et al., 1982, Ashburner et al., 1982, Gubb et al., 1990, Grau et al., 1984, Roote et al., 1996) l(2)k04207 (BDGP Project Members, 1994-1999) ms(2)34Fe (Gubb et al., 1990, Roote et al., 1996)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Df(2L)A48 embryos show defective neuroblast asymmetry. (Cai et al., 2001) Chromosome has no effect on the physical interaction between tandemly duplicated copies of w⁺ and z¹, despite having breakpoints within the critical region. (Gubb et al., 1990) Dominantly causes tergite defects in less than 50% of run³ heterozygotes. (Duffy et al., 1996) Embryos have severe neural defects. (Ashraf et al., 1999)
Position Effect Variegation Data

Stocks ( 3 )
Bloomington	3213 Df(2L)A48, b¹ cn¹ bw¹/CyO
Kyoto	106921 Df(2L)A48, b¹ cn¹ bw¹/CyO 101356 CyO, Cy¹ dp^lv1 Adh^nB pr¹ cn² / Df(2L)A48, b¹ cn¹ bw¹
Notes on Origin
Discoverer	Aaron.
	selected as ADH null on 1-penten-3-ol.
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	Reported to delete Adhr in error; see FBrf0141768 for correction. (Roote et al., 1996)
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	3213 (Eriksen et al., 2000) A48 (Ashburner et al., 1999.10.12, Fossett et al., 1994) Df(2L)A48 (Munro et al., 2006, )
Name Synonym	Deficiency (2L) Aaron
Secondary FlyBase IDs

References ( 31 )

Generate a list of	All references relating to this aberration ( 31 )

List References by type	Research paper ( 24 ) Personal communication to FlyBase ( 3 ) FlyBase analysis ( 1 ) Computer file ( 1 ) Thesis ( 1 ) Book ( 1 )
Recent research papers ( 1 )
	Munro et al., 2006, J. Cell Biol. 172(4): 577--588 A repeated IMP-binding motif controls oskar mRNA translation and anchoring independently of Drosophila melanogaster IMP. [FBrf0190940] Show all research papers ...